Download full results files from Dyscovr, as analyzed in publication. Files contain results for all tested driver and target genes and include raw regression output, including driver mutation coefficient values, t-statistics, standard error, and p-values. If you use these files in your own work, we ask that you please cite:
Geraghty, S., Boyer, J.A., Fazel-Zarandi, M., Arzouni, N., Ryseck, R., McBride, M., Parsons, L.R., Rabinowitz, J., Singh M. (2026). Driver-associated transcriptional rewiring reveals conditional genetic vulnerabilities in cancer. bioRxiv.

Download all pan-cancer genetic interaction predictions. These files were generated using a regression model applied to data from The Cancer Dependency Map (DepMap) and run across significant driver mutation-target dysregulation pairings identified by Dyscovr. All predicted genetic interactions are given, with those that are predicted to be acquired interactions or those that are predicted to be amenable to co-targeting labelled. See publication Figure 4 for details.